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  • SGI-1027: A Next-Generation DNA Methyltransferase Inhibit...

    2025-10-23

    Explore how SGI-1027, a potent DNA methyltransferase inhibitor, uniquely modulates cancer epigenetics through CpG island demethylation and DNMT1 degradation. This article delves into advanced mechanisms and applications of quinoline-based DNMT inhibitors in modern cancer research.

  • Z-LEHD-FMK: Decoding Caspase-9 Inhibition in Apoptosis Pa...

    2025-10-22

    Explore the scientific frontier of Z-LEHD-FMK, a selective and irreversible caspase-9 inhibitor, and its pivotal role in dissecting mitochondria-mediated apoptosis. This in-depth analysis uncovers advanced applications and molecular insights not found in conventional reviews.

  • α-Amanitin: Advanced Strategies in RNA Polymerase II Inhi...

    2025-10-21

    Explore α-Amanitin’s unique role as a potent RNA polymerase II inhibitor in advanced transcriptional regulation research. This in-depth article reveals underexplored applications in RNA stability and epigenetic studies, providing new insights beyond conventional workflows.

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